Heart Failure - Systolic Dysfunction [2017 new]

[2017 new]

Introduction to this self-study CME activity


Over the past decade, the understanding of HF has changed dramatically.  The most common cause of HF remains an ischemic insult.  This insult initiates a cascade of events mediated by neurohormonal influences that adversely affect the heart.   Numerous pharmacologic and lifestyle interventions can improve mortality.  The availability of so many treatments has resulted in confusion about how and in whom to initiate and titrate therapy, resulting in variation in the management of this condition and under use of medications that have been proven effective.  

Health care systems have targeted HF as a medical condition needing better disease-based management because of its prevalence and its management costs.   Treatment guidelines have evolved to improve the standardization of care using evidence-based approaches.  This guideline-based, self-study activity provides practical guidance to clinicians about managing heart failure due to systolic dysfunction.  A framework of symptom severity guides pharmacologic treatment of these patients.

Participants in this CME activity will understand and be able to implement evidence-based cost-effective clinical strategies for the diagnosis and treatment of heart failure in adults.  


This self-study activity is appropriate for primary care clinicians and other health care providers who diagnosis and treat heart failure in adults.


Team Leaders

  • William E. Chavey, MD
    Family Medicine

Team Members

  • Barry E. Bleske, PharmD
  • R. Van Harrison, PhD
    Medical Education
  • Robert V. Hogikyan, MD, MPH
    Geriatric Medicine
  • Yeong Kwok, MD
    General Medicine
  • John M. Nicklas, MD


  • Todd M. Koelling, MD

Author Disclosures

Neither the team lead, the team members, nor the consultants have financial relationships with commercial companies whose products are discussed in this CME activity.
Barry Bleske, PharmD
Speaker's Bureau
Boehringer Ingelheim
Speaker's Bureau
Research Funding
William E. Chavey, MD
R. Van Harrison, PhD
Robert V. Hogikyan, MD, MPH
Yeong Kwok, MD
John M. Niklas, MD

Other Acknowledgements

UMHS Guidelines Oversight Team

  • Grant Greenberg, MD, MA, MHSA
  • R. Van Harrison, PhD

Literature Search Services

  • Taubman Health Sciences Library

Production of Internet Format and Website Maintenance

  • Ellen Patrick-Dunlavey, MA

CME Accreditation and Credit Designation

The University of Michigan Medical School is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

The University of Michigan Medical School designates this enduring material for a maximum of 1 AMA/PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

This CME activity was prepared for release in February 2017. CME credit may be awarded for a maximum of three years from its release date, specifically from February 2017 through January 2020. Continuation of credit from that date depends on a thorough review of the content currency and accuracy.

Method of Participation

  1. View the web pages. You may print the self-study text to read off-line.
  2. Complete the on-line learning assessment test with a score of 70% or higher.  After you initially take the test, the test will be immediately electronically scored. 
    If fewer than 70% of the questions are answered correctly, the questions that were not answered correctly will be noted in red.  Review the CME content related to those topics and retake the test.
    If 70% or more of the questions are answered correctly, the correct and incorrect answers for all questions will be shown along with explanations of the basis for the correct answer.  The link to register and receive credit is shown at the end of the items and explanations. 
  3. Complete the electronic credit request and activity evaluation.  An electronic certificate of participation will be provided immediately.
  4. Print the certificate of participation for your personal records.